Water the pine cone cactus sparingly, allowing the soil to completely dry in between waterings. The best method of irrigation is to soak the succulent completely and then allow to dry. Plant in a terra cotta pot to absorb excess moisture.
It tolerates poor soil, but prefers sandy, well-draining soil. Full sun to partial shade is required for this species, and as such it fares better outdoors. However, if providing direct light, indoor planting is possible, but growth may be reduced under insufficient sunlight.
It can be propagated through seed, but as the species grows slowly, stem cuttings or layering are recommended instead. The most simple method of propagation is by the pinecone-like segments, which can be easily detached and replanted. However, if propagating from seed, plant in well-draining soil – do not plant outside if the environment is cool. Even when mature, this plant is cold tender and can only survive down to 15° F - USDA hardiness zones 8b to 10b - for brief periods of time.
Lastly, wear gloves when handling to prevent damage by the glochids, and transplant carefully, as the pinecone-like segments are very fragment and prone to breaking off.